Recent advances in treatment of severe primary immunodeficiencies [version 1; referees: 2 approved]

Primary immunodeficiencies are rare, inborn errors that result in impaired, disordered or uncontrolled immune responses.Whilst symptomatic and prophylactic treatment is available, hematopoietic stem cell transplantation is Laundry Detergent an option for many diseases, leading to cure of the immunodeficiency and establishing normal physical and psychological health.Newborn screening for some diseases, whilst improving outcomes, is focusing research on safer and less toxic treatment strategies, which result in durable and sustainable immune function without adverse effects.

New conditioning regimens have reduced the risk of hematopoietic stem cell transplantation, and SELENO EXCELL- SELENIUM 200MCG new methods of manipulating stem cell sources should guarantee a donor for almost all patients.Whilst incremental enhancements in transplantation technique have gradually improved survival outcomes over time, some of these new applications are likely to radically alter our approach to treating primary immunodeficiencies.

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